var MongoClient = require('mongodb').MongoClient;

var url = "mongodb://localhost:27017/";

​

MongoClient.connect(url, function(err, db) {

  if (err) throw err;

  var dbo = db.db("mydb");

  //Delete the "customers" collection:

  dbo.collection("customers").drop(function(err, delOK) {

    if (err) throw err;

    if (delOK) console.log("Collection deleted");

    db.close();

  });

});

​